Teledyne Isco announces the introduction of RediSep Rf Gold high performance silica columns, giving organic chemists the flexibility to run purifications optimized for resolution or optimized for speed. Utilizing patent-pending small, spherical silica media, RediSep Rf Gold columns allow you to run your separations in two different modes, Gold Resolution or Gold Speed.

Gold Resolution mode is used for closely eluting compounds that don’t typically separate on standard Flash-grade silica gel columns. The superior media can handle difficult purifications such as trace compounds and isomers. Gold Resolution mode uses the same method settings as a standard column on most Flash chromatography systems - simply replace your column with a higher performance Rf Gold silica column.

Gold Speed method is used on compounds where resolution is not as critical. Gold Speed lets you run at higher flow rates with steeper gradient profiles. Thanks to the advantages of small, spherical media you will see sharper peaks. You can shorten your run times by an average of 60%, and save 30% or greater on solvent usage. Your purifications will be more concentrated in 2/3 fewer fractions, which means reduced drying times. Gold Speed mode is also a good way to protect your silica-sensitive samples.

When compared to standard flash chromatography columns, RediSep Rf Gold silica columns provide better resolution, without high backpressure. High backpressure from irregular media columns can limit the flow rate on lower pressure flash systems, thereby increasing purification run times.

Most chromatography systems can be programmed to duplicate Gold Resolution and Gold Speed modes. However, Teledyne Isco’s CombiFlash® Rf systems use RFID detection to automatically recall optimized methods preset for each mode and column size.

RediSep Rf Gold media includes normal phase silica, C18, amine, cyano, and diol functionalized silica gels. Column sizes range from 4 grams to 1500 grams for easy scale up on all chemistry. To see the resolving power and speed of RediSep Rf Gold silica columns, visit us on the web at www.isco.com/rfgold.


For additional information, contact Teledyne Isco,
4700 Superior St., Lincoln, NE 68504
Toll Free (800)228-4373; Tel (402)464-0231;
Fax (402)465-3064; e-mail iscoinfo@teledyne.com.